CONCLUSIONS: Our qualitative findings can help support Veterans Health Administration (VHA)'s efforts to anticipate reproductive healthcare services needed for both men and women. A better understanding of the contextual factors impacting post-military fertility intentions can support VHA's Whole Health approach-understanding what matters to the person, not what's the matter with the person-and potentially improve clinician-veteran communication and inform reproductive healthcare policy...

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The STAIR (Stroke Treatment Academy Industry Roundtable) sponsored a workshop during the STAIR XIII conference in Washington, DC on March 27 to 28, 2025, to develop consensus recommendations, particularly regarding research priorities and design elements for trials of reperfusion therapies. This forum brought together stroke neurologists, neuroradiologists, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke, and industry representatives to...

Sleep is essential for human functioning, but little attention has been paid to the interplay between sleep and maladaptive personality traits. We examined genetic and environmental associations between sleep and four maladaptive domains (MDs)-Negative Affectivity, Detachment, Disinhibition, and Psychoticism-within the framework of the DSM-5 Alternative Model of Personality Disorders (AMPD). We estimated phenotypic, genetic, and environmental variance and covariance using a twin study approach....

CONCLUSIONS: Veterans' high satisfaction with this PtDA indicates its potential to encourage firearm safety planning, engage support, and foster firearm safety conversations to prevent suicide among women Veterans.

OBJECTIVE: Status epilepticus (SE) is a neurological emergency requiring immediate treatment. Although intravenous lacosamide (LCM) is used for the management of epilepsy, its effectiveness in treating SE remains unclear. We aimed to compare the in-hospital outcomes between intravenous LCM and levetiracetam (LEV) as an early adjunctive therapy for SE using a nationwide inpatient Japanese database.

CONCLUSIONS AND RELEVANCE: This phase 2 randomized clinical trial failed to demonstrate differential benefits for online cognitive training, a structured cognitive rehabilitation program, and tDCS for cognitive long COVID.

CONCLUSIONS: Integrated care for AUD and concurrent ALD populations can effectively reduce returns to alcohol use and be successfully integrated in a medical setting. The core ingredient of such interventions was the inclusion of an addiction medicine specialist into a medical setting, rather than an outside referral. Strategic telehealth utilization can further reduce geographic and specialty-specific barriers to SUD care in medically ill populations. More consensus is needed on key components,...

CONCLUSIONS: Ipsilateral motor pathways of the external oblique muscles have physiological features unlike those of contralateral motor pathways.

Recent findings suggest that neurodevelopment plays a critical role in Huntington's Disease (HD) pathogenesis. This review integrates data from human studies of children and young adults at risk for HD (the Kids-HD study) with the theory of antagonistic pleiotropy (AP), which posits that genes promoting early-life advantages may confer late-life risks. Longitudinal imaging of gene-expanded (GE) children and adolescents shows that mHTT is associated with larger cortical volumes, enhanced surface...

In human neuroimaging, brain atlases are essential for segmenting regions of interest (ROIs) and comparing subjects in a common coordinate frame. State-of-the-art atlases derived from histology^(1-3) provide exquisite three-dimensional cytoarchitectural maps but lack probabilistic labels throughout the whole brain: that is, the likelihood of each location belonging to a given ROI. Here we present NextBrain, a probabilistic histological atlas of the whole human brain. We developed artificial...

The retrosplenial cortex (RSC) is a critical brain region that is activated during spatial memory tasks and plays a crucial role in the consolidation of long-term memory. Various classes of RSC excitatory neurons across different laminar layers serve as the central hub for neuronal connections between the RSC and other brain regions, such as the hippocampus. Despite the established role of the RSC in spatial memory, the transcriptomic signature of the neuronal subtypes in the RSC during spatial...

CONCLUSIONS: VetCoor supported rural veterans' health care and health-related social needs using dedicated coordinators. This model addresses resource gaps, fosters VA-community collaboration, and aligns with the VA's expanding benefits under the Promise to Address Comprehensive Toxics Act.

CONCLUSIONS: Chronic pain is common among individuals with CFS/ME and is associated with diminished quality-of-life. Although not all individuals with CFS/ME experience chronic pain, a prominent proportion do.

CONCLUSION: It is imperative that providers be knowledgeable about buprenorphine and how to optimize it for OUD as well as pain. Pain management with buprenorphine can be tailored to the patient and clinical situation, but any therapeutic plan must contain a holistic approach and involve extensive communication that includes the patient and all relevant providers to achieve safe and effective care.